Berberine occurs naturally in plants such as barberry, goldenseal, goldthread, philodendron tree, and turmeric. It has an unpleasant taste and is yellow in color. While its prominence as a dietary supplement has increased in recent years, berberine has been used for therapeutic purposes for a very long time. For instance, traditional Chinese medicine utilized berberine to treat a variety of medical conditions. Currently, berberine is utilized most frequently to treat diabetes, excessive cholesterol, and high blood pressure. Its ability to aid weight reduction has contributed to berberine's popularity as a natural weight control supplement.

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Berberine is typically administered orally as a tablet or powder. It enters the circulation via the digestive system prior to reaching the body's cells. Berberine binds to molecular targets, thereby altering their function, which can affect how the body responds to particular health issues. In addition, Berberine stimulates the AMP enzyme, also known as the metabolic master switch. This enzyme is present in a variety of organs, including the brain, heart, liver, kidneys, and muscles, and plays an essential role in regulating metabolism.

<a>How does it work?[/b]
Several hundreds of investigations on Berberine have now been conducted.
According to animal studies, one of the primary Berberine effects of berberine is to activate AMP-activated protein kinase within cells (AMPK).
This enzyme is present in every cell of the body and plays a vital role in regulating metabolism and energy levels.
Berberine may also influence the activation or inactivation of genes, thereby protecting against a variety of chronic diseases.

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